OCT in the elderly application of early diagnosis of glaucoma.doc

OCT in the elderly application of early diagnosis of glaucoma Abstract Objective To detect the retinal nerve fiber layer thickness (RNFL) and optic disc structural parameters, combined with visual field changes of optical correlation tomography (OCT) in glaucoma early diagnosis. Methods OCT 10 eyes of normal subjects, 34 eyes of patients with suspected glaucoma, chronic angle-closure glaucoma (CACG) in patients with early and mid-scan and 36 to the optic disc to the optic nerve center of a circle, a diameter of 3.4 mm circular scan, observed in each group OCT image features of the crowd. Subjects in each group were compared each quadrant RNFL thickness, optic disc horizontal, vertical cup ratio and cup / disc area ratio, mean RNFL thickness and visual field index for linear regression and correlation analysis. OCT test results normal, suspected glaucoma, and CACG among the three groups of the early and mid-quadrant RNFL thickness, the optic disc parameters were significantly different (P lt;0.05). The average RNFL thickness and visual field mean defect values (MD) and was a strong positive linear relationship. Conclusion OCT RNFL thickness and can be an early reflection of changes in optic disc and visual field examination with a good correlation can be used as method of early diagnosis of glaucoma. Keywords: OCT; retinal nerve fiber layer thickness; cup ratio; glaucoma; diagnosis Chronic angle-closure glaucoma (Chronic angle closure glaucoma, CACG) occult disease, the majority of patients suffered serious damage to visual function until only find serious irreversible blinding eye disease. Visual field changes in the past that the visual function of glaucoma is to determine the gold standard. But Quigley and other 1 that when retinal ganglion cell death ingt; 50% of the above, the view was changed. When the decline in retinal light sensitivity of 5 dB, the more than 20% of the retinal ganglion cell death 2. Therefore, the optic disc in glaucoma,