Of anesthesia and cytokine balance of function and content of.docVIP

 PAGE \* MERGEFORMAT 12 Of anesthesia and cytokine balance of function and content of Abstract: This paper described a balanced anesthesia and cytokine function and meaning, based on the combined analysis of the status quo from a different angle in anesthesia applications of cytokine balance. Keywords:: anesthesia; cell factor; balance Preface is currently widely used in clinical anesthesia induction and maintenance, local anesthesia-assisted sedation, outpatient anesthesia and short surgical ICU patient sedation and other fields. A large number of studies have shown that propofol on perioperative heart, lung, brain, liver and kidneys and other vital organs have a certain degree of protection. In recent years, with the neurophysiology, molecular biology, on the propofol cerebral protection and regulation of cytokine balance mechanism of action of the research is continued to deepen. 1. Anesthesia and cytokine balance of function and meaning Cytokines by activated macrophages, monocytes, lymphocytes, endothelial cells, fibroblasts, platelets, etc. produced by a group of highly biologically active small molecule peptides. Is the cytokine interleukin-important category. Most of cytokines in monomer form, as a cell signaling factor-mediated immune response and inflammatory reactions are also involved in the regulation of hematopoiesis. Paracrine secretion of cytokines normally secreted in the form of or from acting on nearby cells or cytokine-producing cells themselves, in some cases, a small number of inflammatory cytokines can also be in the form of endocrine-like role in the distant parts of the target organ, a small number of cytokines in order to transmembrane form (such as TNF-α ) and membrane-bound form (such as IL-8) directly on adjacent target cells. Cytokines and hormones, neuropeptide, neurotransmitter together constitute the intracellular signaling molecule systems, in signal transduction, receptor regulation and multiple levels of biological effec