Occupational dermatitis type of drug eruption.docVIP

Occupational dermatitis type of drug eruption Abstract: Occupational exposure to certain chemicals can cause exfoliative dermatitis, bullous epidermal necrolysis, severe erythema multiforme and erythema multiforme, often accompanied by fever and mucosal damage, in severe cases involving the viscera, similar to the eruption. In this paper, the occupational disease chemicals, pathogenesis, clinical manifestations, diagnosis, prognosis and naming, etc. are reviewed. Occupational exposure to certain chemicals due to systemic generalized exfoliative dermatitis, severe erythema multiforme (Steven-Johnson Syndrome), and bullous epidermal necrolysis springing skin disease, often accompanied by fever and liver and kidney, etc. organ damage, severe cases, death. Because of its shape-specific, serious condition, the disease-causing materials and relatively concentrated in the trichlorethylene, pesticides and dimethyl dithiocarbamate, while an increasing number of clinicians and health doctor’s attention. An occupational disease-causing chemicals Reported so far have been caused by occupational diseases in this group of disease-causing chemicals, primarily TCE, 1605, dimethoate, methamidophos, farmers think of it, dimethyl dithiocarbamate and acrylonitrile, etc. [1 ~ 21]. 1.1 TCE (acetylene of chloroform, Trichloroethylene, TCE) Chemical formula CHClCCl2, colorless liquid, with smell like chloroform, molecular weight 131.4, boiling point 86.7 ℃. Insoluble in water, soluble in ethanol, ether and other organic solvents. With a strong degreasing effect, mainly used as degreasing agents, extraction agents, solvents, pesticides are also used in the preparation, organic synthesis, clothes, dry cleaning and so on. It can be used by the respiratory tract, digestive tract, and skin absorption. This product can cause a large number of short-term exposure in order to suppress the central nervous system disorder mainly system