Of different doses of glucocorticoid treatment efficacy analysis of paraquat poisoning.docVIP

 PAGE \* MERGEFORMAT 9 Of different doses of glucocorticoid treatment efficacy analysis of paraquat poisoning Author: Bai Changqing, Yue-Zhong, ZHANG Xi-gang, Sun written, Qiu Wu, cattle arts, Yuan Xin, Li Yan, Xiao-Bo Peng [Abstract] Objective: To compare different doses of glucocorticoid treatment of paraquat (PQ) poisoning clinical effect. Methods: A nested case-control research program. According to inclusion criteria were from 136 out-patient medical records in the test group composed of 23 cases (large dose group), according to matching criteria, medical records taken out from the remaining 46 cases formed the control group (conventional-dose group). test group using high-dose methylprednisolone Long shocks and long maintenance treatment with dexamethasone treatment, the control group with conventional dose glucocorticoid treatment. analysis and comparison of two groups of patients with mortality, survival time, survival curves and causes of death. Results: The two groups of patients with admission basically the same as the main clinical features of the test group of patients with mortality rate of 65.2% (15 / 23), control group 73.9% (34/46), compared with no statistical difference between the two groups (P = 0.34), two groups of patients, the average survival time [(21.3 ± 10.3) d vs (17.6 ± 10.4) d , P = 0.17] and the survival curves (P = 0.24) and no statistical difference. two groups of patients with respiratory failure is the first cause of death. Conclusion: High-dose glucocorticoid treatment of poisoning in the PQ value to be further clinical observation. [Keywords:] paraquat; poisoning; glucocorticoids; case-control study [Abstract] AIM: To investigate the effect of different dosage of steroid on treatment of paraquat poisoning. METHODS: A nested case  control study was designed. Retrospective analysis of 136 patients admitted with a diagnosis of paraquat poisoning over the last 3 years was performed . The experimental group (n = 23) re