Of puerarin on the treatment of cardiovascular diseases in vitro.docVIP

 PAGE \* MERGEFORMAT 6 Of puerarin on the treatment of cardiovascular diseases in vitro [Abstract] Objective To review the treatment of cardiovascular diseases puerarin pharmacological studies and clinical research. Methods papers related literature database search, select the part of the high-quality research papers generalize, sorting, summing up. The results of puerarin on coronary heart disease, hypertension, arrhythmia, viral myocarditis, heart failure and other cardiovascular diseases has a good effect. Conclusion Puerarin for the treatment of cardiovascular diseases has a good effect, should be further strengthened to avoid its adverse reactions, dosage forms, etc. Studies designed to further expand its clinical application. [Keywords:] puerarin Clinical Pharmacology Study of Cardiovascular Disease Puerarin from the dried roots of legume Pueraria lobata isoflavones to achieve a mention. Its main components are 8-D-glucopyranosyl 4,7-dihydroxy-isoflavone, formula C21H20O9, molecular weight of 416 [1], commonly used in the treatment of hypertension, coronary heart disease, angina and other cardiovascular diseases, in recent years, continuously expand the clinical application, this paper puerarin treatment of cardiovascular diseases in recent years, pharmacological research and clinical application to do a review. 1 Pharmacological Research 1.1 pairs of blood pressure and heart rate effects of puerarin on the normal and high-pressure animals can produce good antihypertensive effect, it can reduce the conscious spontaneously hypertensive rats (SHR) and normal blood pressure and slow down the dog anesthesia heart rate, 50 cases of high - Pur intravenous blood pressure patients also confirmed that they have the role of blood pressure and a slower heart rate, and renin - angiotensin system inhibition, but also reduce the levels of catecholamines, suggesting that its antihypertensive effect and suppression of renin - blood vessel angiotensin system and redu