Of type 2 diabetes status and control strategies.docVIP

 PAGE \* MERGEFORMAT 20 Of type 2 diabetes status and control strategies Keywords: Type 2 diabetes prevention and treatment strategy Because of lifestyle changes (nutrition, excess, lack of exercise, etc.) and the acceleration of population aging in 2003, China has become the world’s third largest country of diabetes, diabetic patients after India [1]. Prevalence of diabetes in China from 1986 (0.9%) to 1994 (2.5%) rapidly increased nearly 3-fold [2], is currently close to 40 million diabetics. According to the latest report of the Ministry of Health, this growth trend will lead to increase in 3000 cases of our new patients a day, an annual increase of 1.2 million patients with diabetes [3], of which 90% of type 2 diabetes mellitus (T2DM). But the people of the diabetes awareness, treatment, and compliance rates were lower than in developed countries. Because T2DM is a chronic progressive disease, will inevitably lead to various complications, increased disability, mortality. Many factors can speed up the metabolism of a variety of complications of T2DM, of which the most serious cardio-cerebral vascular diseases. High blood sugar, blood lipid abnormalities, high free fatty acid (FFA) and insulin resistance (IR) leading to vascular endothelial dysfunction, followed by chronic inflammation of vascular smooth muscle dysfunction, accelerated atherosclerosis (AS) formation. In addition, changes in platelet function, so that platelet aggregation, fibrinolysis system to be abnormal, leading to reduced anticoagulant mechanism, forming AS plaques shedding induced thrombosis. These lesions can sometimes precede the occurrence of clinical diabetes [4]. Based on the above understanding, prevention and treatment strategies in patients with T2DM should be focused on a single hypoglycemic, but should also change unhealthy lifestyles and improve quality of life, concerned about the lipid-lowering, antihypertensive, anti-platelet and anti-inflam