Pairs of nasal continuous positive airway pressure ventilation combined with ambroxol treatment of neonatal respiratory distress syndrome.docVIP
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Pairs of nasal continuous positive airway pressure ventilation combined with ambroxol treatment of neonatal respiratory distress syndrome
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Pairs of nasal continuous positive airway pressure ventilation combined with ambroxol treatment of neonatal respiratory distress syndrome
[Abstract] Objective: To investigate the primary hospital for pairs of nasal continuous positive airway pressure (CPAP) and ambroxol hydrochloride in combination treatment of neonatal respiratory distress syndrome (NRDS) the efficacy and clinical value. Methods: 23 cases in children with CPAP ventilation NRDS the same time to the intravenous injection of ambroxol hydrochloride plus atomization treatment, observation of blood oxygen saturation before and after treatment, X-ray and clinical effects. Results: Compared with before treatment, medication or after 6 h SpO2 was significantly higher at 12 h, 24 h, 36 h SpO2 remained steady at a high level, the difference was statistically significant. Medication 6 h, respiratory distress symptoms in 4 cases (17.4%), significant improvement in 18 cases (78.3%), did not reduce the 3 cases; 48 h later, X-ray showed significant improvement in the transparency of 18 cases of lung field (78.3%). 23 cases were cured 20 cases (87%), 1 patient died, two cases of the families of the signature giving up treatment. Conclusion: CPAP and ambroxol hydrochloride in combination treatment of NRDS satisfactory clinical results, cost-effective, compliance is good, is worth at the grassroots level to promote the hospital.
[Keywords:] ambroxol hydrochloride; pulmonary surfactant; pairs of nasal continuous positive airway pressure ventilation; respiratory distress syndrome
Neonatal respiratory distress syndrome (NRDS) is due to premature child due to lack of pulmonary surfactant (PS) caused by neonatal intensive care unit (NICU) in one of the main causes of death in premature children. Currently in the Western developed countries and China’s most economically developed regions with pulmonary surfactant (PS, Curosurf) mechanical ventilation for treatment, but economically underdeve
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