Patients with ischemic cerebrovascular disease of hepatocyte growth factor level and its clinical significance.doc

 PAGE \* MERGEFORMAT 13 Patients with ischemic cerebrovascular disease of hepatocyte growth factor level and its clinical significance Study: When Xu Zhongxin Zhao Mingming Wang Yu Tu Chien Wang Haiyan Ma Ming Zhao Qing [Abstract] Objective To study the hepatocyte growth factor (HGF with ischemic cerebrovascular disease (ICVD relationship and explore its content and its clinical significance. Methods 65 cases detected by quantitative ELISA ICVD patients (with acute brain injury (ACI group of 39 patients , transient ischemic attack (TIA group, 26 patients) and 25 normal control group, levels of serum HGF, carotid artery recorded ICVD thickness (IMT, ACI infarct lesion size, neurological deficit score. Results ICVD patients Serum HGF levels were significantly higher, ACI was significantly higher than the TIA group (P lt;0.05, large, medium and small cerebral infarction group was significantly higher in patients with ACI and ACI patients with different infarct group was significantly different between groups ( both P lt;0.05, mild, moderate and severe neurological deficits ACI serum HGF levels were significantly different (P lt;0.05, while the severe group and the moderate group was not significant (Pgt; 0.05.ICVD patients IMT values, spot block was significantly higher than those detected positive (P lt;0.05, different degrees of carotid atherosclerosis (AS) ICVD serum HGF levels were significantly higher (P lt;0.05,3-level, 2 AS set neck with one significant difference between groups (P lt;0.05, but the three groups with two groups was not significant (Pgt; 0.05. Conclusion ICVD serum HGF levels were significantly increased, in ACI was significantly higher in patients with early onset, and infarct volume , ischemic severity, ICVD ICVD serum HGF levels and the type and AS degree. [Keywords:] ischemic cerebrovascular disease (ICVD), hepatocyte growth factor (HGF), atherosclerosis Ischemic cerebrovascular disease (ICVD) in the pathogenesis, diagnosis an