Perinatal intrauterine infection on the impact of children.doc

 PAGE \* MERGEFORMAT 13 Perinatal intrauterine infection on the impact of children [Abstract] intrauterine infection of mother to child transmission, also known as congenital infection or disease, is infected pregnant women during pregnancy caused by infection of the fetus in the womb. Intrauterine infection can cause a lot of pathogenic microorganisms, most of virus infection. Palace The main route of transmission of infection are: (1) the vertical transmission of the placenta; (2), ascending genital tract infection spread; (3) perinatal infection. perinatal infection and include childbirth, breastfeeding, and neonatal directly contact. Clinical diagnostic criteria: maternal fever, body temperature 37.5 , maternal heart rate greater than 100 times / min, fetal heart rate greater than 160 times / min, the smell of amniotic fluid, uterine tenderness, peripheral blood WBC greater than 15 109 / L , CRP greater than 8mg / L. satisfy the above condition 3 or more clinical criteria. infections occur more than in early pregnancy cause miscarriage, congenital malformation, the third trimester of infections lead to premature delivery, premature rupture of membranes, neonatal infection , cerebral palsy and other adverse consequences, is the child of perinatal morbidity, mortality and maternal morbidity, increased mortality reasons. Thus, according to different periods of active infection control is very important. [Keywords:] intrauterine infection; perinatal children Intrauterine infection or infected mother to child transmission, also known as congenital diseases, pregnant women during pregnancy is caused by infection of the fetus in the womb infection. Big difference in the incidence, the current reported clinically significant incidence of intrauterine infection in 0.5 % ~ 10%. Soper et al [1] reported the incidence as high as 4% to 10.5%. domestic large survey found that newborns in our country a high incidence of congenital infection, reaching 5%, the har