Pharmaceutical Analysis masking discussion.doc

 PAGE \* MERGEFORMAT 10 Pharmaceutical Analysis masking discussion [Abstract] method of drug analysis with examples of drug analysis are discussed in the masking problem, and consider the type of drug analysis of masking interference component can be divided into component masking masking method and tested method. [Keywords:] drug analysis masking Drug analysis often there is the coexistence of other components, these components tend to interfere with the measured coexistence of the analysis of drugs, for which masking is frequently used methods to eliminate the interference of coexisting components. On masking in general textbook [1] believe that the method according to reaction types of masking ligand masking method, oxidation-reduction masking masking method and precipitation method in pharmaceutical analysis in fact not just the above-mentioned three kinds of mask types, but also Other types of masking. I believe that type of drug analysis of masking interference component can be divided into component masking masking method and tested method. Be discussed separately below for reference. An interference component masking method The traditional use of a masking agent masking coexisting ions interfere with the actual measurement method is the most commonly used method of a class, often applied a masking agent and coexistence ions interfere with redox reactions, precipitation reactions and coordination reaction [1]. In pharmaceutical analysis coexistence interference with the use of a masking agent masking components, this interference component may be ions or compounds, masking reaction may not necessarily be the above-mentioned three kinds of types of masking response, the actual drug analysis work, some organic reactions (such as an increased into the reaction, Schiff reaction and acylation reaction, etc.) can also be used as a masking reaction. 1.1 Addition Reaction of interfering component masking method using a masking agent and co-existence interf