Pharmacodynamic study of herpes-ling.doc

 PAGE \* MERGEFORMAT 7 Pharmacodynamic study of herpes-ling Author: Chen Peng, Yang Lichuan, LEI Wei-Ya, Zhang 61, Zhi-Qiang Shen 【Abstract】 Objective To observe the herpes spirits analgesic, anti-itching and anti-infection effect. Methods acetic acid-induced writhing method in mice and in mice Evaluation of Formaldehyde damage of herpes spirits of the tickle response to analgesic effect and impact; to histamine phosphate hanging-drop method to stimulate the dorsum of guinea pig after damage was observed in this product the role of the anti-local damage; use of xylene-induced mouse ear swelling method to explore the goods swelling anti-infection effect.The results of herpes Ling significantly reduced the number of writhing induced by acetic acid in mice and reduce injury in mice due to formaldehyde after licking biting time for foot and vaginal device; this product significantly reduced the total amount of histamine phosphate to raise guinea pigs induced itch threshold;4 times the clinical dose of herpes Spirit There is a definite improvement in the role of xylene-induced mouse ear edema. Conclusion herpes Ling has obvious analgesic, anti-itching effect, but also have some anti-inflammatory effects, the skin after topical are conducive to disease herpes pain, itching and other symptoms improved. Keywords: Herpes Ling; analgesic; itching; anti-infection 【Abstract】 Objective To investigate effects of abirritation, relieving itching and anti-inflammation on Paozhenling.Methods Effects of Paozhenling on abirritation was tested by using of ache model caused by acetic acid or formaldehyde in mice.The method of giving hanging drop of histamine phosphate on dorsum of foot in guinea pig was used to investigate anti-injury effect of Paozhenling. Anti-inflammation effect was determined by using of auricle tumefaction mice caused by dimethylbenzene.Results Paozhenling obviously decreased the quantity of body wrest caused by acetic acid and