Pill Qizhi blood on refractory nephrotic syndrome of hypercoagulability.doc

 PAGE \* MERGEFORMAT 7 Pill Qizhi blood on refractory nephrotic syndrome of hypercoagulability [Keywords:] nephrotic syndrome; hypercoagulable state, blood pill Qizhi Nephrotic syndrome (IINS) and more associated with hyperviscosity, blood is hypercoagulable state, the clinical treatment more difficult, less effective and the relapse rate is high. Therefore, to improve blood coagulation status, for improving the IINS cure and prevent recurrence of great significance to May -2006 .2004 In June, I use the hospital blood preparations Qizhi IINS pill on patients were 82 cases of clinical observation, are reported below. 1 Materials and Methods 1.1 The diagnostic criteria of refractory nephrotic syndrome [1] ① proteinuriagt; = 3.5 g / d, ② hypoalbuminemia (serum albumin lt;30 g / L), ③ edema; ④ hyperlipidemia. Which ①, ② essential items, and on the glucocorticoid invalid or dependent on hormone therapy, or a 3-year recurrence, relapse within six months, more than 2 times. 1.2 The diagnostic criteria of hypercoagulability There is no uniform diagnostic criteria. Refer to the related paper [2], formulated the following criteria: prothrombin time (PT) compared with normal reference values #8203;#8203;(11 ~ 14 s) reducedgt; 3 s, kaolin partial thromboplastin time (APTT) than the normal reference values #8203;#8203;(35 ~ 45 s) reducedgt; 10 s, plasma fibrinogen (Fbg)gt; 4.0 g / L, plasma D-dimer (DD)gt; 0.5 mg / L. After the two or more consistent . excluded gastrointestinal ulcers, deep vein thrombosis, bleeding tendency and before treatment and other diseases have been used within 15 d of heparin and other anticoagulant drugs and traditional Chinese medicine are. 1.3 General Information Patients were enrolled 158 patients, are in hospital in May 2004 -2006 outpatients and inpatients in June were divided into treatment group and control group. The treatment group 82 cases, 49 males and 33 females, aged 10 to 61 years an average of 42 years of