Pill Xiaoliu and lung epithelial cells in human lung cancer PG cells cadherin α-Catenin and β-catenin expression and its significance.doc

 PAGE \* MERGEFORMAT 12 Pill Xiaoliu and lung epithelial cells in human lung cancer PG cells cadherin α-Catenin and β-catenin expression and its significance On: Sun Zheng Jiang Yanling Wang Lingling new paragraph Fan Zhou [Abstract] Objective To study the pill on removing tumor and lung epithelial cells cadherin (E-cadherin), @-catenin and β-catenin in human lung cancer cell lines in PG expression and its significance. Methods Immunohistochemistry Streptomyces avidin - peroxidase method (SP) detection of human lung cancer PG cells E-cadherin, @-catenin and β-catenin in the pill interfere with removing tumor and lung expression under. randomly divided into 4 groups that consumer tumor and lung pill high dose group, tumor and lung pills consumer low dose group, clearing the lungs phlegm pill group and the control group. Results E-cadherin and @-catenin, β-catenin in tumor and lung Pill Consumer positive rate under different, in which E-cadherin in tumor and lung pill consumption under the influence of low positive rate was significantly lower than clearing the lungs phlegm pill group and the blank (P lt;0.01); and @-catenin, β-catenin in removing tumor protection Under the intervention of pulmonary pill positive rate was higher than clearing the lungs and phlegm pill group and control group (P lt;0.01). Conclusion removing tumor and lung pill on E-cadherin, @-catenin and the expression of β-catenin significant, suggesting that the invasion and metastasis of lung cancer has a certain inhibitory effect, thus indicating that E-cadherin, @-catenin and β-catenin expression and lung cancer progression and metastasis. [Keywords:] removing tumor and lung pills; epithelial cells cadherin; @ - catenin; β-catenin; human lung cancer PG cells; immunohistochemistry Metastasis of lung cancer patients is an important reason leading to one death. Adhesion in the process of tumor metastasis is a key link, in which adhesion molecules play an indispensable role. Epithel