Placental site trophoblastic tumor in 2 cases of clinical features and treatment.docVIP

 PAGE \* MERGEFORMAT 12 Placental site trophoblastic tumor in 2 cases of clinical features and treatment [Abstract] Objective: To investigate the placental site trophoblastic tumor (PSTT clinical and pathological features and treatment. Methods: 2 cases of clinical data of patients with PSTT. Results: PSTT may be secondary to all types of pregnancy, clinical manifestations dripping bleeding after menopause the main pathological features of a large number of abnormal proliferation of intermediate trophoblast cells, vascular infiltration, increased serum HCG is not obvious, and more than 1 000U / L, immunohistochemistry HPL, EMA, CK moderate to strongly positive, HCG weak. Conclusion : PSTT is a rare trophoblastic tumor, diagnosis must rely on pathological features, treatment, though with surgery, but chemotherapy can achieve the fertility treatment and retention effect. [Keywords:] placental site trophoblastic tumor, clinical and pathological features, treatment Abstract Objective: To study the clinicopathologic features and treatment of placental site trophoblastic tumor (PSTT). Methods: 2 cases of PSTT were collected for study. Results: PSTT is a kind of disease which can be secondary to pregnancy, with vagina bleeding as the notable clinical manifestation. It presents such pathological features as trophoblastic cell proliferation, notable blood vessel infiltration, less remarkable HCG rise, intensively positive HPL, EMA and CK in immunohistochemical straining and faint HCG. Conclusion: As a rare tropho blastic tumor, PSTT has its particular characteristics of microscope and its diagnosis mainly rely on pathologic features. Chemotherapy can be taken to achieve the purpose of treating and keeping reproduction though operation is the leading measure of treatment. Keywords: PSTT; Clinicialpathoiogy; Treatment. Placental site trophoblastic tumor (PSTT is a rare gestational trophoblastic tumor (GTN, no specific clinical features, accounting for GTN