Plasma NTproBNP in elderly patients with diastolic heart failure in patients with early diagnosis.doc

 PAGE \* MERGEFORMAT 12 Plasma NTproBNP in elderly patients with diastolic heart failure in patients with early diagnosis Study: Guohua Tao Xu Lihua Zhang Yuanzhuo Lvshu Jie [Abstract] Objective To investigate the plasma amino-terminal B-type natriuretic peptide (NT proBNP in elderly patients with diastolic heart failure (DHF patients with early diagnosis. Methods 26 patients with normal heart function examination as control group, a clear diagnosis of heart contraction failure (SHF patients (LVEF lt;50% 25 cases of DHF normal heart chamber group (LVEFgt; = 50%, E / A 122 DHF cases and 28 cases heart enlargement. ELISA method for the determination of plasma NT proBNP concentrations. Results (1NYHA heart functional class and NT proBNP concentrations were significantly correlated (r = 0.658, P lt;0.01, LVEF and NT proBNP concentrations were significantly negatively correlated (r =- 0.608, P lt;0.01, NYHA classification differences between NT proBNP levels are statistically significant (P lt;0.01. (2 heart failure, plasma NT proBNP levels were significantly different between the groups (P lt;0.01. Conclusions The plasma NT proBNP can be used as an objective evaluation of the severity of heart failure indicators, especially for early diagnosis of DHF and more value. [Keywords:] plasma NT proBNP, elderly diastolic heart failure, early diagnosis N-terminal B-type natriuretic peptide (NT proBNP) is the ventricular muscle cells to secrete B type Natriuretic Peptide (BNP) produced when an equimolar neurohormonal, ventricular end diastolic volume or pressure increase can promote the synthesis and release. heart failure, ventricular wall tension increases, can plasma BNP and NT proBNP levels, significantly higher than normal, the majority of cardiovascular disease, chronic heart failure is the final outcome, but also one of the leading causes of death. heart failure, including systolic and diastolic heart failure, systolic heart failure (SHF) increased when t