Post ointment eczema borneol and menthol inclusion process of_0.doc

 PAGE \* MERGEFORMAT 9 Post ointment eczema borneol and menthol inclusion process of OF: He Qun Zhao Biqing Xu Xiaoli Dai-hua Yang Zhibo [Abstract] Objective Optimization eczema ointment paste borneol and menthol inclusion of the optimal process parameters. Ways to borneol and menthol for the evaluation of process indicators, both gas chromatography content. By grinding the inclusion, Screening the best orthogonal design parameters. The results of β-cyclodextrin plus 2 times the amount of water, grinding time 1.0 h, 35 ℃ inclusion complex prepared by drying of borneol and menthol inclusion volume content of the highest. Conclusion The conditions for the preparation of paste creams eczema borneol, menthol β-cyclodextrin the optimal parameters. [Keywords:] eczema ointment paste; borneol; menthol; Inclusion Abstract: ObjectiveTo optimize the borneol, menthol inclusion eczema cream paste.MethodsBorneol and of menthol as the evaluation indexes, the gas phase chromatography was adopted to determine the contents. Grinding method was used for inclusion, orthogonal design select the best process parameters. ResultsThe optimal process was as follows: β-cyclodextrin plus 2 times that of water, grinding time 1 hour, 35 ℃ under dry inclusion complex preparation.ConclusionThe conditions is the best for the production of eczema cream paste borneol, menthol β-cyclodextrin inclusion compound. Keywords:: Eczema cream paste; Borneol; Menthol; Inclusion complex Post eczema ointment composition containing borneol (mainly D-borneol d-Borneol) and menthol (ie, menthol), the two respective fields volatile, low boiling point, room temperature or sublimation, so the preparation of medicines, particularly external preparation, storage period unstable, volatile, resulting in decreased efficacy, so the use of β-cyclodextrin (β-CD) to borneol and menthol for inclusion, inclusion made help to improve stability, to better play a therapeutic role. has been reported by grindin