Pravastatin combined coronary heart disease Tongxinluo Capsule Clinical observation of patients with hypertension and pulse pressure.doc
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Pravastatin combined coronary heart disease Tongxinluo Capsule Clinical observation of patients with hypertension and pulse pressure
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Pravastatin combined coronary heart disease Tongxinluo Capsule Clinical observation of patients with hypertension and pulse pressure
OF: He Zhiwei, Yu Peng description, Lu Bangfu
[Keywords:] pravastatin; Tongxinluo capsule; coronary heart disease; Hypertension; pulse pressure; C-reactive protein
August 2007 -2009 in June, the author of 63 cases of hospital out-patient Department of Cardiology, coronary heart disease in hypertensive patients as objects, observe the pravastatin control of the joint capsule Tongxinluo the role of pulse pressure, are reported below.
1 Materials and Methods
1.1 Case selection criteria
Choice is regular use of antihypertensive medication treatment of coronary heart disease patients with hypertension, taking drugs, including aspirin, nitrates, metoprolol, enalapril, amlodipine equality, use of antihypertensive medication for 6 months, blood pressure is stable, not taking any lipid lowering drugs and Chinese medicines for promoting blood circulation. coronary heart disease diagnosis in 1979 the International Society of Cardiology and the World Health Organization has developed diagnostic criteria of coronary heart disease, some patients confirmed by coronary angiography; The diagnosis of hypertension established in 1999 with reference to the diagnostic criteria of hypertension [1]. selected pulse pressuregt; = 60 mm Hg (1 mm Hg = 0.133 kPa), serum cholesterol 4.66 ~ 6.8 mmol / L. exclude secondary hypertension, acute coronary syndrome, arrhythmia, heart valve disease, peripheral vascular disease and other serious diseases systems.
1.2 General Information
63 patients were randomly divided into conventional treatment group, pravastatin group, pravastatin Tongxinluo joint capsule group (combined group), all 21 patients. The conventional group 10 males and 11 females, aged 53 to 77 years old, average (67.0 + -9.6 years), blood pressure (146/76 + -16 / 8) mm Hg, heart rate (72 + -9) times / min
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