Pregnancy infancy injection of intrauterine infection of hepatitis B immune globulin Effect of blocking.docVIP

 PAGE \* MERGEFORMAT 6 Pregnancy infancy injection of intrauterine infection of hepatitis B immune globulin Effect of blocking [Abstract] mother to child transmission is the major route of transmission of hepatitis B, hepatitis B immunoglobulin during pregnancy for efficient injection and passive infant to take the initiative to block mother to child transmission combined immunodeficiency, for guiding significance of perinatal prevention of the spread of HBV important. [Keywords:] pregnant women; infancy; combined immunodeficiency; interrupt mother to child transmission Hepatitis B virus is a serious hazard to human health worldwide epidemic. China is a high incidence of endemic area of hepatitis B, HBsAg carriers among pregnant women is 5% ~ 10%, resulting in an infant HBV infection is about 1 / 3 comes from mother to child transmission, so to prevent the spread of HBV during pregnancy has important significance. In recent years, our hospital to carry out a comprehensive screening for pregnant women and the implementation of pregnancy, infancy, intrauterine infection of immune globulin injections to reduce work and achieved good results, are summarized below. 1 Data and methods 1.1 General information summarized in our hospital from 2004 to 2005 to 3562 cases of pregnant women attending hospital occurred to carry 270 cases of hepatitis B infection rate of 6.9%. Where: 152 cases occurred in 2005 compared with 2004 increased by 44% of 118 cases, aged 22 to 36 years old,HBeAg infection was 54 cases, accounting for 20%; Xiao Sanyang 113 cases, accounting for 41%; carriers of 103 cases , accounting for 39%. 1.2 Diagnostic criteria of chronic HBV carriers meet the diagnostic criteria in October 2000 session of the National Viral Hepatitis diagnostic criteria [1]. 1.3 combined immune pregnant women infected with HBV voluntary acceptance of HBIG intervention group of 82 cases, 70 cases of the control group. Pregnant women in the intervention group w