Pregnancy itchy skin progress of Chinese and Western medicine treatment.docVIP

 PAGE \* MERGEFORMAT 12 Pregnancy itchy skin progress of Chinese and Western medicine treatment [Keywords:] pregnancy itching treatment of skin disease pathogenesis During pregnancy, due to endocrine, immune function changes, leading to skin and appendages of some physiological or pathological changes occur, the skin itching is one of the most common clinical symptoms, often occurs in 7 to 9 months of pregnancy, as reflected in trunk Lord of the diffuse nature of intense itching, its pathogenesis remain unclear. Known pregnancy intrahepatic cholestasis (intrahepatic cholestasis of pregnancy, ICP) is one of the causes of their disease. Gestation placenta produce large amounts of endogenous estrogen and progesterone hormones, can lead to intrahepatic cholestasis of bilirubin, bile salts stimulate the skin, resulting in itching. Itching dermatosis of pregnancy also includes papules and plaques of pregnancy itchy rash, pruritic folliculitis of pregnancy, pregnancy and other polymorphous rash. In recent years, Chinese and Western medicine diagnosis and treatment of itchy skin disease of pregnancy has made some progress, are summarized below. An intrahepatic cholestasis of pregnancy ICP is an important complication of pregnancy, its pathogenesis is unclear, may be related to estrogen and progesterone hormones and genetic factors. Clinical to the skin characterized by itching and cholestasis of different races, regions there are significant differences in its incidence, ICP high incidence of Chile, about 4%, other countries is about 0.1% ~ 0.2% [1]. ICP main pathological damage to the liver cells cholestasis, hepatic lobule central bile stained, there is no inflammatory cell infiltration and interstitial proliferation. ICP diagnostic kit may refer to music editor of ‘Obstetrics and Gynecology’ [1], usually have the following clinical features: ① jaundice with or without systemic itching, often onset in the 28 ~ 32 weeks pregnant, some as early as 12 weeks were of