Primary lung cancer DMBT1 gene expression in.docVIP

 PAGE \* MERGEFORMAT 16 Primary lung cancer DMBT1 gene expression in Author: Wen Hai Van, Roson ancient, LI, He Jian-initiative 【Abstract】 Objective To investigate the primary lung cancer tissue levels of DMBT1 gene expression in the clinical and pathological features of lung cancer relationship. Methods RT  polymerase chain reaction (RT  PCR) detection of primary lung cancer in the DMBT1 gene expression level. Results 37 cases of primary lung cancer in 10 cases of DMBT1 expression in normal (27.03%, 10/37), there are 27 cases of DMBT1 expression in low or completely free expression (72.97%, 27/37); DMBT1 expression and primary lung cancer pathological type, TNM staging, smoking history, etc. There was no significant correlation (Pgt; 0.05), but lung cancer, histological grade and lymph node, and (or) the relevance of distant metastasis (P lt;0.01). Conclusion DMBT1 gene expression levels of lung cancer incidence and tumor cell differentiation and whether there is transfer of significantly correlated. Keywords: DMBT1 gene expression in primary lung cancer  polymerase chain reaction, RT - The Expression of DMBT1 Gene in Primary Lung Cancer Keywords:: Primary lung cancer; DMBT1 gene expression; RT  PCR DMBT1 newly discovered in recent years as a possible tumor suppressor gene [1], and its mutational inactivation of a variety of tumors that are considered closely related to the occurrence and development at home and abroad has the relationship between lung cancer and DMBT1 has done some research, and that there are at least two aspects of DMBT1 function, on the one hand and the immune defense and immune to supervise the other hand, with the epithelial cell differentiation [2], this writer, the article had reported that DMBT1 gene in primary lung cancer homozygous deletion of the conditions [3], in order to further explore the DMBT1 gene and primary lung cancer, development and metastasis, the present study, reverse transcripti