Primary ovarian neuroectodermal tumor in 1 case.docVIP

 PAGE \* MERGEFORMAT 4 Primary ovarian neuroectodermal tumor in 1 case [Keywords:] primary ovarian neuroectodermal tumors A medical record Patients, female, 53 years, 2 months ago started right upper quadrant discomfort and hospitalization. Abdominal CT results indicated that the inside of the right ovary and liver can be seen a huge mass, do biopsy, diagnosed as sarcoma. Line chemotherapy several times, but did not improve, so do the resection of tumor. surgery found in the liver, mesentery and omentum are multiple scattered on the small mass, the right ovary shows a huge mass, this mass and the uterus, ureter occurred adhesion. Grossly, pathological examination: the right ovary the size of 4cm 10cm 8cm great mass, the quality associated with a large number of real and extensive bleeding and necrosis. Microscopy: round or oval tumor cells, less nuclear staining cytoplasm deep, tumor cells can be seen 1 to 2 nucleoli, showing that pathological mitotic cells from the fibers into a sheet or nested interval distribution around the blood vessels into a false daisy dough. immunohistochemistry showed the tumor cells positive for NSE, Vimentin-positive , S-100 positive, GFAP, CEN, EMA, CEA and LCA were all negative. pathologic diagnosis: primary ovarian neuroectodermal tumors. 2 Discussion Primary ovarian neuroectodermal tumors (PNET) is the original tumor of neural crest origin that belongs to Ewing sarcoma PNET. Often seen in ovarian teratoma neuroectodermal components, which appear in a single ovarian tumors primitive neuroectodermal tumor very rare. NSE as neuronal markers common tumors, in this case tumor cells and the expression of the original fibers were positive, GFAP as a glial tumor marker highly specific, in this case showed the tumor cells and fiber negative; These results demonstrate that, in this case neuronal tumors, but not glial elements. teratoma as there are some clinical features of a single embryo or cell teratoma [1], a singl