Progress debridement enzyme.docVIP

 PAGE \* MERGEFORMAT 19 Progress debridement enzyme [Abstract] debridement is the use of certain enzymes has the role of exogenous proteolytic enzymes for wound debridement of non-surgical methods, in the decomposition or inactivation of removal of necrotic tissue at the same time, without damaging adjacent normal tissue, are mainly used burns, bedsores and chronic wound treatment. of the research are reviewed. [Keywords:] trauma; protease; debridement; infection AResearch progress of enzymatic debridement HU Wei, WANG Ai min, WANG Jian min (Department 6, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing 400042, China) Abstract: Enzymatic debridement is a nonsurgical method to debride wounds with exogenous proteinases which hydrolyze necrotic and devitalized tissue without damaging the normal adjacent tissue.It is applied mainly in the treatment of burns, pressure ulcer and chronic wounds.The author reviews the current situation and its research progress. Keywords:: trauma; proteinase; debridement; infection Currently the most common clinical approach is still the surgical debridement debridement, the effect depends on the surgeon’s experience and eye contamination and necrotic tissue on the wound to judge. Not thorough debridement is the source of postoperative wound infection, whereas complete debridement and often at the expense of the expense of adjacent normal tissue, resulting in larger defects, delayed healing or even organ dysfunction. surgery would inevitably result in bleeding, and there are a variety of surgical risk, which in some cases (such as In addition to extensive burns of the callus, penetrating wound debridement and wound track complex, etc.) show some limitations. enzymatic debridement (enzymatic debridement) refers to the use of certain protein hydrolysis with exogenous enzymes will necrosis Organizational Breakdown inactivation removed without damage to adjacent normal tis