Purpura nephritis in children and platelet levels of fibrinogen and its clinical significance.doc

 PAGE \* MERGEFORMAT 7 Purpura nephritis in children and platelet levels of fibrinogen and its clinical significance Of: Yang Shaofen, Liao Z Q., Li Su, Lin Yuchan [Abstract] Objective To observe children with Henoch-Schonlein purpura and platelet fibrinogen levels and the relationship between HSPN. Methods purpura allergic purpura nephritis combined 36 cases (study group) and 29 patients without purpura nephritis combined children with allergic purpura (acute and convalescent group of fibrinogen and platelet levels were detected and analyzed. The results observed in acute phase of fibrinogen, platelet levels were significantly higher than the recovery period and the control group (P lt; 0.01), the observation group recovery of fibrinogen, platelet count compared with the control group were not significantly different (P allgt; 0.05), while the control group of patients with fibrinogen, the platelet level in the difference between acute and convalescent also not statistically significant (P allgt; 0.05). fibrinogen and platelet levels in Henoch-Schonlein purpura the process of kidney damage, allergic purpura during the treatment combined anticoagulant antiplatelet therapy may prevent or reduce the allergic purpura in children Concurrent Henoch-Schonlein nephritis. [Keywords:] purpura, purpura nephritis, fibrinogen, platelet Henoch-Schonlein purpura (HSP is a systemic capillary allergic disease, clinical manifestations are skin purpura, joint swelling, pain, gastrointestinal bleeding, and purpura nephritis, in which purpura nephritis (HSPN is a serious complication of HSP, is a common pediatric secondary glomerular diseases. now 65 patients in our hospital in children with HSP fibrinogen (Fib) and platelet (PLT were detected, observe the changes in the relationship with HSPN. 1 Data and methods 1.1 General Information Selected cases to our hospital from January 2004 to December 2008 HSP patients were hospitalized, 65 cases were in the acute