Qin Lian drugs on the use in the metabolic syndrome.docVIP

 PAGE \* MERGEFORMAT 5 Qin Lian drugs on the use in the metabolic syndrome [Keywords:] Scutellaria baicalensis Georgi; Coptis; the drug; medicine compatibility; metabolic syndrome Metabolic syndrome (metabolic syndrome, MS) refers to central obesity with dyslipidemia, hypertension, high blood sugar, insulin resistance (IR) [1] a variety of metabolic components of the pathological state of abnormal accumulation. Belongs to Chinese medicine fatness, wet resistance, dizziness, Diabetes and other syndromes, treatment, multi-purpose drug baicalin, berberine, heat-dampness, Xiehuo detoxification, treatment should MS have similar effect. This paper briefly explored. A lipid-lowering diet Modern pharmacological studies suggest that baicalin, berberine has obvious lipid-lowering effect. Scutellaria flavonoids inhibit glucose in the synthesis of fat; baicalin and aglycones in experimental hyperlipidemic rats can reduce the serum free fatty acids, triglycerides and liver total cholesterol, free cholesterol levels; wogonoside can reduce the serum and liver triglyceride levels; skullcap-Ⅱ can lower serum total cholesterol and liver triglyceride concentration; a variety of aglycones baicalin (baicalein, wogonin, baicalin new hormone, etc.) can also increase serum high-density lipoprotein cholesterol (HDL  C) levels [2]. The berberine berberine (BR) can significantly lower serum triglyceride (TG), total cholesterol (TC) and very low density lipoprotein cholesterol (VLDL  C) content [3]. Two step-down Modern pharmacological studies suggest that baicalin, berberine has a calcium channel blocking effect, but has shown good blood pressure lowering effect [4]. Baicalein also has Angiotensin Ⅱ increased blood pressure caused by the role of [5], berberine peripheral vascular expansion directly, reducing peripheral resistance, increase cardiac output, resulting in lower blood pressure effects [4]. 3, lowering blood glucose, improve insulin resistance Diabetes, Gei