Pulmonary heart disease in patients with C-type natriuretic peptide adrenomedullin and significance of the changes in.docVIP

 PAGE \* MERGEFORMAT 12 Pulmonary heart disease in patients with C-type natriuretic peptide adrenomedullin and significance of the changes in [Abstract] Objective To investigate the C-type natriuretic peptide (CNP) and adrenomedullin (ADM) in patients with chronic pulmonary heart disease in the role and significance. Methods of hospitalization in patients with chronic pulmonary heart disease as the experimental group to the same period in healthy volunteers as a control group, using radioimmunoassay in plasma CNP, ADM level, compared CNP, ADM in the experimental group of 100 patients (chronic lung heart disease with acute exacerbation and clinical remission) and the control group, 60 cases of healthy individuals in the level of change, simultaneous determination of partial pressure of oxygen and carbon dioxide partial pressure of blood. Results (1) chronic pulmonary heart disease with acute exacerbation and clinical remission of the CNP, ADM levels were significantly higher than the normal control group (P amp;lt;0.01); (2) chronic pulmonary heart disease with acute exacerbation of CNP, ADM The content was significantly higher than those of clinical remission (P amp;lt;0.01); (3) in patients with chronic pulmonary heart disease in CNP, ADM and blood oxygen partial pressure was negatively correlated (r = -0.622, -0.702, P amp;lt;0.05), and blood carbon dioxide partial pressure correlation was not obvious (r = 0.205,0.233, Pamp;gt; 0.05); (4) in plasma CNP and ADM were positively correlated (r = 0.279, P amp;lt;0.05). Conclusion CNP, ADM involved in chronic pulmonary heart disease in the pathophysiological process; by observing the plasma CNP, ADM level changes, can reflect the chronic pulmonary heart disease. [Keywords:] C-type natriuretic peptide; adrenomedullin; pulmonary heart disease Changes of plasma c-type natriuretic peptide and plasma adrenomedullin in patients with chronic pulmonary heart disease [Abstract] Objective To explore the role and