Qin in granule quality standard.docVIP

 PAGE \* MERGEFORMAT 5 Qin in granule quality standard [Abstract] Objective To establish the Qin to granules finished product testing quality standards. Methods The thin-layer chromatography (TLC) of the Qin to granule TLC; by high performance liquid chromatography (HPLC) determination of Qin in granule content of baicalin. The results with the TLC method of checking repeatability good; content was determined by high performance liquid chromatography, baicalin content of not less than 2.0%; granule water content by loss on drying method, water content shall not exceed 14%. Conclusion of the test method is simple, accurate, reliable, and can be used as the preparation of quality control methods. [Keywords:] granules baicalin thin-layer chromatography HPLC Qin in granules is a skullcap, habitat, Ophiopogon japonicus, Artemsia argyi compatibility and other traditional Chinese medicine, has a heat dampness, Xiehuo detoxification, Qingreliangxue, Yin Sheng Jin, lungs and pure heart, warm by the bleeding, cold-dispelling pain, the town cough and asthma, dampness itching, Liyan and other effects. For acute pharyngitis, tonsillitis and upper respiratory tract infection embolism. Scutellaria [1] as Fang-jun medicine, baicalin [2] as the main active ingredient, has anti-inflammatory [3], anti-oxidation, blood pressure, sedation, inhibit intestinal peristalsis, blood fat, anti-allergic, antibacterial, anti-virus [4] as well as anti-tumor and other pharmacological effects. In this study, using thin-layer chromatography of the products were qualitatively identified, and application of high-performance liquid chromatographic determination of baicalin content in the preparation of the quality control of scientific and practical approach. An instrument and reagent High Performance Liquid Chromatography (Agilent1100 quaternary pump, DAD detector). Qin ground granules (homemade), baicalin reference substance by the Chinese pharmaceutical and biological products available (f