Quetiapine in the treatment of clinical analysis of 67 cases of senile schizophrenia.docVIP

 PAGE \* MERGEFORMAT 7 Quetiapine in the treatment of clinical analysis of 67 cases of senile schizophrenia [Abstract] Objective: To evaluate quetiapine in the treatment of schizophrenia elderly efficacy and safety. Methods: 67 elderly patients with schizophrenia were treated with oral quetiapine 50 ~ 600 mg / d treatment were observed for 8 weeks. At the treatment 1,2,4,8 weekend before treatment and use of Brief Psychiatric Rating Scale, Positive and Negative Syndrome Scale Assessment of clinical efficacy, adverse side effects rating scale. Results: The markedly effective rate was 73.13% at week 8, the effective rate was 91.04 %; Brief Psychiatric Rating Scale and the Positive and Negative Syndrome Scale score, total score and positive symptoms of psychosis factor score than those from treatment 1 week before treatment was significantly decreased (P lt;0.05), treatment of negative symptoms factor score 2 weekend significantly decreased (P lt;0.05), and with the extension of treatment time showed a continuous decline; adverse reactions were drowsiness. Conclusion: Quetiapine treatment of schizophrenia were significantly older, rapid onset, high security, compliance good. [Keywords:] quetiapine; old; Schizophrenia Quetiapine is a new atypical antipsychotic. Home and abroad have reported efficacy of quetiapine in the treatment of schizophrenia is better, its not only positive symptoms and negative symptoms and effective, cognitive and affective symptoms are also effective [ 1-2]. Compared with conventional antipsychotics, because of its adverse reactions less well tolerated and suitable for elderly patients with schizophrenia. quetiapine in order to further validate the clinical efficacy of the treatment of schizophrenia and old age security, We conducted clinical observations, are reported below. 1 Subjects and methods 1.1 The subjects selected from April 2008 to April 2009 in our hospital of elderly patients with schizophrenia in this study. Inc