Radiofrequency ablation at all levels of bronchial.doc

 PAGE \* MERGEFORMAT 5 Radiofrequency ablation at all levels of bronchial [Abstract] Objective: To observe the pathological changes at all levels of bronchial explore the effects of radiofrequency ablation of the bronchial, to provide the basis for its clinical application. Methods: 6 healthy domestic pigs were divided into two groups, for percutaneous radiofrequency ablation of normal lung tissue respectively ablation 3 d and 28 d after the slaughter of three observed shape and size of the ablation zone and the performance at all levels of bronchial pathology. Results: 28 d when the damage zone biopsy ablation significantly less than the maximum diameter of 3 d, when (t = 2.853 , P = 0.017). With the smaller bronchial cavity, RF aggravated injury to the bronchial; right main bronchus, secondary bronchus less damage. the main bronchus, secondary bronchus 28 d after ablation to restore better. two or more bronchial fistula does not appear. Conclusion: Radiofrequency ablation for the bronchial injury in less than two, and are available at the 28d returned to normal, is a relatively safe minimally invasive treatment of lung cancer. [Keywords:] Catheter ablation of bronchial 0 Introduction With inactivated tumor cells, for the purpose of eliminating tumor burden Minimally invasive local ablation therapy has attracted wide attention in recent years, radical surgery for the loss of regular access to treatment in patients with solid tumors provides a new treatment option [1]. Which, CT guided percutaneous lung puncture cold polar radio frequency ablation of lung cancer has been widely used in clinical and achieved remarkable clinical results, but close to the heart, esophagus, large trachea, large blood vessels of the lesions, as easy to damage these structures, limiting this part of lesion treatment [2-4]. With regard to radiofrequency ablation for the impact of the heart and great vessels have been reported that the aorta near the heart or lung tumors can be the