Qingzao quality standard mixture of lungs.doc

 PAGE \* MERGEFORMAT 13 Qingzao quality standard mixture of lungs Of: Zhou Juanjuan, Pankin fire, Lu Huan, Zhu peace, Pan [Abstract] Objective To establish the quality standard mixture Qingzao lungs. Methods of preparation of thin layer chromatography mulberry, licorice, littoralis, Ophiopogon japonicus, loquat qualitative identification, using high performance liquid chromatography preparation glycyrrhizic acid were determined. TLC negative results without interference, specific, and glycyrrhizic acid in 0.203 1 ~ 1.692 1 μg good linear relationship, r = 0.999 8, average recovery was 98.24%, RSD = 2.62% . Conclusion This method is simple, fast, reproducible, and can be used for quality control mixture Qingzao lungs. [Keywords:] Qingzao lungs mixture, quality standards, glycyrrhizic acid, HPLC, TLC Keywords:: Qingzao Runfei Mixture; quality standard, glycyrrhizic acid, HPLC, TLC Qingzao lungs mixture by the leaf, gypsum, licorice root, black sesame, littoralis, Ophiopogon japonicus, loquat composed of 9 herbs taste. Qingzao lungs with effect for the dry gas lung injury, dry cough without sputum, gas inverse Erchuan, dry nose and throat, upset thirst and other symptoms. Author based on physical and chemical properties of drug prescription composition [1] and repeated tests, on mulberry leaves, licorice, littoralis, Ophiopogon japonicus, loquat were identified, also was determined by high performance liquid chromatography preparation of glycyrrhizic acid, the establishment of a reliable, stable, simple quality control method. An instrument and reagent Agilent1100 HPLC, Agilent1100 UV detector, HP Chemstations workstations. Qingzao mixture of 10 batches of samples from the lungs and Yangzhou Pharmaceutical Co., Ltd. to produce and three drugs provided (batch 061101,061102,061103,061104,061105, 061106,061107,061126,061128,061130), licorice herbs purchased from Yangzhou City, medicine company (from Yangzhou Pharmaceutical Co., Ltd. to provide