Recent research on Parkinsons disease MRI.doc

 PAGE \* MERGEFORMAT 13 Recent research on Parkinson’s disease MRI Of: Zhao Dan River Huang Mao Biography million new Tanglan Ying Zhou Yun Zhang Xiong Yan Zhihan [Keywords:] Parkinson’s disease, magnetic resonance imaging (MRI, functional magnetic resonance imaging (fMRI Parkinson’s disease (parkinson’s disease, PD is a common neurodegenerative disease, the prevalence rate increased with the aging population increases, the current diagnosis of PD depends on the clinical manifestations and drug response against PD, Some studies have shown, PD onset error diagnosis rate within 5 years of 15% to 25%, although PET and SPECT has been shown for the diagnosis and early diagnosis of PD, but because of its relative complexity and operating expensive equipment, while requires a lot of technology and biometrics support, in clinical application is limited. In comparison, MRI more than make up for deficiencies, and hospitals in the country has been more widely used in recent years, on the MRI studies of PD, There are many reports, this paper is to start from the MRI, introducing diagnosis, secondary diagnosis of PD and its condition assessed in several ways. 1 PD in patients with substantia nigra width measurement Brain was uneven distribution of iron, according to the paramagnetic effect of iron, containing high levels of iron with organizations such as the substantia nigra pars reticulata (SNr), the red nucleus in T2 weighted images (T2WI showed low signal, while the more low concentration of iron with organizations such as the substantia nigra (SNc is showed equal signal (1,2), the performance of the corresponding plane has been confirmed by histological sections (1). by measuring between the two low-signal areas such as signal width is the width of substantia nigra obtained. As PD of the main lesion in the SNc, studies have shown that PD patients with elevated iron levels within the SNc, showed pathological iron deposition (3,4), abnormal deposition of i