Regular infusion of mitomycin bladder care to prevent the recurrence of bladder cancer.docVIP
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Regular infusion of mitomycin bladder care to prevent the recurrence of bladder cancer
PAGE \* MERGEFORMAT 8
Regular infusion of mitomycin bladder care to prevent the recurrence of bladder cancer
Of: first, the United States Peng, Lu Yunjie, Xudong Zhen, Lin Qiuyi
[Keywords:] intravesical bladder cancer care
Our hospital from July 2005 ~ December 2007, conducted by transurethral resection of bladder tumor (TURBT) + mitomycin C on a regular basis after treatment of superficial bladder perfusion of 60 cases of bladder cancer, and achieved satisfactory results, are as follows.
Clinical data
1. General Information
The group of 60 cases, 50 cases were male and 10 female, aged 21 to 86 years, mean age 54 years, starting both cases, preoperative tumor biopsy by cystoscopy and pathology confirmed bladder transitional cell carcinoma of the G1 ~ G2 level , of which 45 cases of single and multiple in 15 cases, tumor diameter 0.5 ~ 3.0 cm, are used TURBT surgery.
2. Methods
2 weeks after reperfusion, week 1, a total of 6 times, then 1 every 2 weeks, a total of 6 times, and then 1 month, maintained until after 2 years. Method is to mitomycin 20 mg [1] diluted in normal saline 30 ml [2], through the urethra into the bladder, 15 min changing body position (supine, left side, right side, prone, keep 2 h after discharge. the implementation of each bladder perfusion during treatment routine urine examination is required before the first 1 year of liver every 3 months, renal function and cystoscopy, 2 years 6 months of every such examination 1, cystoscopy examination for pathological examination of suspicious tissue.
3. Results
All patients in this group insisted on bladder treatment, patients were followed up 3 months to 2 years, 6 patients from 3 months to 12 months, recurrence rate of 10% and relapse patients were re-line TURBT and intravesical therapy, up to a routine surgery 3 times, 4 patients with different degrees of bladder irritation or lower abdominal discomfort, after a lot of water go away, without making other treatmen
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