Resonance light scattering technique in drug analysis.doc

 PAGE \* MERGEFORMAT 18 Resonance light scattering technique in drug analysis [Abstract] resonance light scattering technique for determination of drugs and analysis of biological macromolecules and its application are reviewed. Focuses on the method in the analysis of drugs in biological fluids and application prospects of Chinese medicines. Is a large body molecule drugs and other medicines detection method provides a new way. [Keywords:] resonance light scattering technique; Pharmaceutical Analysis Abstract: The application and the development of the resonance light scattering (RLS) method used in drug determination and the biomacromolecule determination was reviewed. The application of RLS in pharmaceutical quantification in biological fluids, and the application of RLS in quantification of Chinese medicine were reviewed . This method might be a novel way for the determination macromolecular drugs and other medicinal ingredients in vivo. Keywords:: resonance light scattering; pharmaceutical quantification Resonance light scattering (resonance light scattering, RLS) is the use of common fluorescence spectrophotometry to measure the scattering of a light scattering analysis [1]. The technology because of its simple, fast and sensitive analysis of the characteristics of attracting life science , analytical chemistry, environmental science, materials science and other fields of theory and application of its workers, conducted in-depth research, and promote the analysis of intra-disciplinary links between the various branches, especially in the chemical and biological areas has made some achievements [ 2]. Widespread phenomenon of light scattering particles in the process of interaction of light and, when the medium particle diameter (d) with the incident light wavelength (0) exists d 0.05 0, the produce is Rayleigh (Rayleigh) scattering-based The molecular scattering of light [3]. According to RLS theory can be obtained with the scattering of