Restore Bitongning capsules anti-inflammatory effects and mechanisms of.doc

 PAGE \* MERGEFORMAT 4 Restore Bitongning capsules anti-inflammatory effects and mechanisms of [Abstract] Objective To study the anti-inflammatory to restore Bitongning capsule and its effects on inflammatory tissue prostaglandin 2 (PGE2) content of impact. Methods carrageenan-induced rat paw edema and xylene-induced ear swelling in mice and rat models of acute inflammation granuloma model of chronic inflammation anti-inflammatory effect, and detection of inflammatory tissue PGE2 content. Results restore Bitongning capsules have anti-inflammatory effect on the xylene-induced mouse ear edema, rat carrageenin-induced paw edema and rat granuloma have different degrees of inhibition, and can significantly reduce the inflammatory tissue PGE2 content. Conclusion Reduction Bitongning capsules have anti-inflammatory effects, its anti-inflammatory mechanism of inhibiting inflammatory mediators PGE2 production. [Keywords:] to restore the anti-inflammatory prostaglandins Bitongning capsule 2 Chinese herbal compound preparation to restore the Bitongning capsule from the Tianshan snow lotus, saffron, Speranskia tuberculata, pangolins, Millettia, Tianma, Clematis, Achyranthes, 37 etc., with Qufeng cold-dispelling, warm through the meridians, promoting blood circulation Huayu the effectiveness of clinical practice mainly for the treatment of rheumatism, rheumatoid arthritis, rheumatism, cold joint pain, gout, ankylosing spondylitis Yandeng disease. That party for many years used clinically apparent effect. This study further to provide a safe and effective for clinical experimental evidence, to restore the anti-inflammatory Bitongning capsule and its effects on inflammatory tissue prostaglandin 2 (PGE2) concentration effects were studied. 1 Materials 1.1 Drugs and reagents to restore Bitongning capsules, often restored Beijing Bio-Technology Co., Ltd. product, batch number 070,105; Wantong bones film, Tonghua Wantong Pharmaceutical Co., Ltd. product, lot number 070422F;