Risperidone combined sodium valproate treatment of aged-control study of mania.doc

 PAGE \* MERGEFORMAT 9 Risperidone combined sodium valproate treatment of aged-control study of mania [Abstract] Objective To study the combined risperidone and chlorpromazine were sodium valproate treatment of senile mania efficacy and side effects. Approach would be consistent with diagnostic criteria of CCMD-3 of 56 cases of various types of elderly manic patients were randomly divided into two groups based on the use of sodium valproate were combined risperidone or chlorpromazine in the treatment for 8 weeks. Results Risperidone in the treatment group significantly the efficiency of the first week 4,8, respectively 69.2% and 88.4%, efficiency 84.5%, 96.1% and chlorpromazine were similar; but the former in a weekend rate (23%) Low on the latter (53.3%). Conclusion risperidone combined with sodium valproate treatment of elderly manic valproate combined with chlorpromazine similar overall efficacy and safety, compliance and higher, suitable for elderly patients. [Keywords:] risperidone; chlorpromazine; sodium valproate; mania; old The lack of sodium valproate as a mood stabilizer and anti-psychiatry rapid sedative effect that might be of clinical in most patients with acute manic episodes when combined antipsychotics [1]. Studies have shown that risperidone combined mood stabilizer in acute mania satisfactory effect. In this paper, risperidone and chlorpromazine were combined sodium valproate treatment of elderly patients with manic efficacy and safety control study conducted. An object and methods 1.1 Object randomly selected 56 cases in April 2005 ~ June 2006 in our hospital outpatient and inpatient treatment of elderly manic patients were recruited. Comply with the CCMD-3 in single manic episode, recurrent mania, bipolar disorder, manic phase of the diagnostic criteria and the BRMS pre-treatment total score ≥ 6 points. To exclude drug and alcohol dependence, cerebral organic diseases, liver and kidney disease, who are known for risperidone, ch