Ru Yi Jin Huang San Filmogen Improvement.doc

 PAGE \* MERGEFORMAT 9 Ru Yi Jin Huang San Filmogen Improvement [Abstract] Objective To chitosan-graft-poly methyl methacrylate as a film-forming material was prepared by Ru Yi Jin Huang San Remover to release more homogeneous than the original Filmogen and durable. Ruyi Golden Powder method taking into account the main components of the solubility, solvent extraction with ethanol as active ingredients, in order to chitosan-graft-methyl methacrylate copolymers as film-forming material preparation Remover, HPLC determination of turmeric Remover Su, rhein, emodin, chrysophanol, berberine content. The results in the release of rhein Filmogen degree evaluation index, Filmogen release effect in vitro than by chitosan as film-forming material better. Conclusion Chitosan-g-methyl methacrylate copolymers as film-forming material preparation Ru Yi Jin Huang San Remover flexible and better, rhein in vitro release effect is more obvious. [Keywords:] Ruyi golden powder; chitosan-graft-methyl methacrylate; film; berberine; curcumin; Rhein Abstract: ObjectiveTo prepare Ruyijinhuangsan film with Chitosan-graft-poly (Methyl Methacrylate) in order to release medicine more uniformly and more lastingly than former film. MethodsThe effective components from the Ruyijinhuangsan powder were extracted with alcohol considering the solubility of the main components in Ruyijinhuangsan . The film was prepared with Chitosan-graft-poly (Methyl Methacrylate) and the constituents of curcumin, rhein, emodin, chrysophanol, berberine in the film were determined with HPLC. ResultsThe release rate of Rhein in film was better than that of former film . ConclusionRuyijinhuangsan film prepared with Chitosan-graft-poly (Methyl Methacrylate) is more flexible and has better characteristics of sustained-release in vitro than former film. Keywords:: Ruyijinhuangsan; Chitosan-graft-poly (Methyl Methacrylate); Film; Berberine; Curcumin; Rhein Ru Yi Jin Huang San from 10 Chinese herbal medicines, con