Tumor lymphangiogenesis and lymph node metastasis.docVIP

 PAGE \* MERGEFORMAT 15 Tumor lymphangiogenesis and lymph node metastasis [Abstract] lymph node metastasis is an important way to tumor metastasis, but also key indicators of prognosis. As the lymphatic endothelial markers found on how to induce tumor lymphangiogenesis and lymph node metastasis for tumors to become the research hotspot. Now and its regulation in tumor lymphangiogenesis, lymphatic endothelial markers, as well as lymphangiogenesis and tumor metastasis aspects are reviewed. [Keywords:] tumor lymphangiogenesis and lymph node metastasis Tumor lymph node metastasis is the most difficult to treat cancer, resulting in the death of the important reasons for the assessment of whether or not there is lymph node metastasis in the prognosis of patients with significant value. But has a number on how tumor cells induce tumor-related lymphangiogenesis and promote lymph node metastasis and tumor cells how to escape from the primary tumor and how to enter the lymphatic research. But with the discovery of lymphatic markers, tumor lymphangiogenesis and lymph node metastasis has become a new hotspot. In this paper, and its regulation in tumor lymphangiogenesis, lymphatic endothelial markers, as well as lymphangiogenesis and tumor metastasis, etc. are reviewed. A tumor lymphangiogenesis and its regulation Lymphatic metastasis of tumor cells, the main way. Therefore, the study of lymphatic vessels in tumor tissue and its regulation in generating factors on the study of tumor lymph node metastasis significance. In mature organizations, lymphatic capillaries lymphatic vessels from the existing way on to budding growth, with new blood vessels from the capillaries or capillaries vein similar to the budding growth. However, if there are new tumor lymphatic vessels and functional lymphatic vessels in dispute. 1  1 in tumor tissue distribution of functional lymphatic vessels and structural characteristics of Padera et al [1] study speculated that the lack of functi