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Clinicopathologic features and outcomes following surgery for pancreatic adenosquamous carcinoma.doc

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Clinicopathologic features and outcomes following surgery for pancreatic adenosquamous carcinoma

World Journal of Surgical Oncology BioMedCentral Research Open Access Clinicopathologic features and outcomes following surgery for pancreatic adenosquamous carcinoma Jun-Te Hsu1, Han-Ming Chen2, Ren-Chin Wu3, Chun-Nan Yeh1, Ta-Sen Yeh1, Tsann-Long Hwang*1, Yi-Yin Jan1 and Miin-Fu Chen1 Address: 1Department of Surgery, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan, 2Department of Surgery, Chung Shan Medical University Hospital, Chung Shan Medical University, Taichung, Taiwan and 3Department of Pathology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan Email: Jun-Te Hsu - hsujt2813@.tw; Han-Ming Chen - ming1838@; Ren-Chin Wu - gby@.tw; Chun- Nan Yeh - ycn@.tw; Ta-Sen Yeh - tsy471027@.tw; Tsann-Long Hwang* - hwangtl@.tw; Yi- Yin Jan - janyy@.tw; Miin-Fu Chen - chenmf@.tw * Corresponding author Published: 3 September 2008 Received: 26 May 2008 Accepted: 3 September 2008 World Journal of Surgical Oncology 2008, 6:95 doi:10.1186/1477-7819-6-95 This article is available from: /content/6/1/95 ? 2008 Hsu et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Pancreatic adenosquamous carcinoma (ASC) is a rare pancreatic malignancy subtype. We investigated the clinicopathological features and outcome of pancreatic ASC patients after surgery. Methods: The medical records of 12 patients with pancreatic ASC undergoing surgical treatment (1993 to 2006) were retrospectively reviewed. Survival data of patients with stage IIB pancreatic adenocarcinoma and ASC undergoing surgical resection were compared. Results: Symptoms included abdominal pain (91.7%), body weight loss (83.3%), anorexia (41.7%) and jaundice (25.0%).