Classication of Forefoot Plantar Pressure Distribution in Persons with Diabetes A Novel Perspective for the Mechanical Management of Diabetic Foot.docVIP

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Classication of Forefoot Plantar Pressure Distribution in Persons with Diabetes A Novel Perspective for the Mechanical Management of Diabetic Foot.doc

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Classication of Forefoot Plantar Pressure Distribution in Persons with Diabetes A Novel Perspective for the Mechanical Management of Diabetic Foot

ClassificationofForefootPlantarPressureDistributionin PersonswithDiabetes:ANovelPerspectiveforthe MechanicalManagementofDiabeticFoot? KevinDeschamps1,2,3*,GiovanniArnoldoMatricali3,4,PhilipRoosen1,KaatDesloovere1,2, HermanBruyninckx5,PieterSpaepen5,FrankNobels6,JosTits6,MiekeFlour3,7,FilipStaes1 1Department of Rehabilitation Sciences, Katholieke Universiteit Leuven, Leuven, Belgium, 2Laboratory for Clinical Motion Analysis, University Hospitals Leuven, Pellenberg, Belgium, 3Multidisciplinary Diabetic Foot Clinic,University Hospitals Leuven, Leuven, Belgium, 4Department of Development Regeneration,Katholieke Universiteit Leuven, Leuven, Belgium, 5Department of Mechanical Engineering, Katholieke Universiteit Leuven, Leuven, Belgium, 6Department of Internal Medicine- Endocrinology,Onze-Lieve-VrouwZiekenhuisAalst,Aalst,Belgium,7DepartmentofDermatology,UniversityHospitalsLeuven,Leuven,Belgium Abstract Background:Theaimofthisstudywastoidentifygroupsofsubjectswithsimilarpatternsofforefootloadingandverifyif specificgroupsofpatientswithdiabetescouldbeisolatedfromnon-diabetics. Methodology/PrincipalFindings:Ninety-sevenpatientswithdiabetesand33controlparticipantsbetween45and70years wereprospectivelyrecruitedintwoBelgianDiabeticFootClinics.Barefootplantarpressuremeasurementswererecorded and subsequently analysed using a semi-automatic total mapping technique. Kmeans cluster analysis was applied on relativeregionalimpulsesofsixforefootsegmentsinordertopursueaclassificationforthecontrolgroupseparately,the diabetic group separately and both groups together. Cluster analysis led to identification of three distinct groups when consideringonlythecontrolgroup.Forthediabeticgroup,andthecomputationconsideringbothgroupstogether,four distinctgroupswereisolated.Comparedtotheclusteranalysisofthecontrolgroupanadditionalforefootloadingpattern wasidentified.Thisgroupcompriseddiabeticfeetonly.TherelevanceofthereportedclusterswassupportedbyANOVA statisticsindicatingsignificantdifferencesbetwe