TimeDelay-ARACNE Reverse engineering of gene networks from time-course data by an information theoretic approach 英文论文文献.docVIP

Zoppoli et al. BMC Bioinformatics 2010, 11:154 /1471-2105/11/154 METHODOLOGY ARTICLE Open Access TimeDelay-ARACNE: Reverse engineering of gene Methodology article networks from time-course data by an information theoretic approach Pietro Zoppoli1,2, Sandro Morganella1,2 and Michele Ceccarelli*1,2 Abstract Background: One of main aims of Molecular Biology is the gain of knowledge about how molecular components interact each other and to understand gene function regulations. Using microarray technology, it is possible to extract measurements of thousands of genes into a single analysi