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TNF-α Mediates Eosinophil Cationic Protein-induced Apoptosis in BEAS-2B Cells 英文论文文献
Changetal.BMCCellBiology2010,11:6
/1471-2121/11/6
RESEARCH ARTICLE
OpenAccess
TNF-aMediatesEosinophilCationicProtein-
inducedApoptosisinBEAS-2BCells
Kun-CheChang1?,Chih-WeiLo1?,Tan-chiFan2,MargaretDah-TsyrChang2,Chih-WenShu1,Chuan-HsinChang1,
Cheng-TaChung1,Shun-lungFang2,Chih-ChungChao1,Jaw-JiTsai3,Yiu-KayLai1,4*
Abstract
Background:Eosinophilicgranulocytesareimportantforthehumanimmunesystem.Manycationicproteinswith
cytotoxicactivities,suchaseosinophilcationicprotein(ECP)andeosinophil-derivedneurotoxin(EDN),arereleased
fromactivatedeosinophils.ECP,withlowRNaseactivity,iswidelyusedasabiomar
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