Toll-like receptor gene polymorphisms are associated with susceptibility to graves ophthalmopathy in Taiwan males 英文论文文献.docVIP
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Toll-like receptor gene polymorphisms are associated with susceptibility to graves ophthalmopathy in Taiwan males 英文论文文献
Liaoetal.BMCMedicalGenetics2010,11:154
/1471-2350/11/154
RESEARCH ARTICLE
OpenAccess
Toll-likereceptorgenepolymorphismsare
associatedwithsusceptibilitytoGraves’
ophthalmopathyinTaiwanmales
Wen-LingLiao1,2,Rong-HsingChen3,Hui-JuLin4,Yu-HueiLiu1,2,Wen-ChiChen5,YuhsinTsai2,LeiWan1,2,6*,
Fuu-JenTsai1,2,6*
Abstract
Background:Toll-likereceptors(TLRs)areafamilyofpattern-recognitionreceptors,whichplaysaroleineliciting
innate/adaptiveimmuneresponsesanddevelopingchronicinflammation.ThepolymorphismsofTLRshavebeen
associatedwiththeriskofvariousautoimmunediseases,includingsystemiclupuserythematosus(SLE),
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