Toll-like receptor ligands induce the expression of interferon-gamma and interleukin-17 in chicken CD4+ T cells 英文论文文献.docVIP

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Toll-like receptor ligands induce the expression of interferon-gamma and interleukin-17 in chicken CD4+ T cells 英文论文文献.doc

Toll-likereceptorligandsinducetheexpressionofinterferon-gammaandinterleukin-17inchickenCD4Tcells英文论文文献

St.Pauletal.BMCResearchNotes2012,5:616 /1756-0500/5/616 RESEARCH ARTICLE OpenAccess Toll-likereceptorligandsinducetheexpressionof interferon-gammaandinterleukin-17inchicken CD4+Tcells MichaelSt.Paul,NedaBarjesteh,SarahPaolucci,YanlongPeiandShayanSharif* Abstract Background:Toll-likereceptors(TLRs)areevolutionarilyconservedpatternrecognitionreceptorsthatmediatehost responsestopathogens.Todate,atleast10differentTLRshavebeenidentifiedinchickensincludingTLR2,which bindslipopeptidesandothersimilarligandssuchasPam3CSK4,TLR3,whichbindsdoublestrandedRNAaswellas syntheticmoleculessuchaspolyI:C,TLR4,

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