Toll-like receptor ligands induce the expression of interferon-gamma and interleukin-17 in chicken CD4+ T cells 英文论文文献.docVIP
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Toll-likereceptorligandsinducetheexpressionofinterferon-gammaandinterleukin-17inchickenCD4Tcells英文论文文献
St.Pauletal.BMCResearchNotes2012,5:616
/1756-0500/5/616
RESEARCH ARTICLE
OpenAccess
Toll-likereceptorligandsinducetheexpressionof
interferon-gammaandinterleukin-17inchicken
CD4+Tcells
MichaelSt.Paul,NedaBarjesteh,SarahPaolucci,YanlongPeiandShayanSharif*
Abstract
Background:Toll-likereceptors(TLRs)areevolutionarilyconservedpatternrecognitionreceptorsthatmediatehost
responsestopathogens.Todate,atleast10differentTLRshavebeenidentifiedinchickensincludingTLR2,which
bindslipopeptidesandothersimilarligandssuchasPam3CSK4,TLR3,whichbindsdoublestrandedRNAaswellas
syntheticmoleculessuchaspolyI:C,TLR4,
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