原创力文档Two Frequenins in Drosophila unveiling the evolutionary history of an unusual Neuronal Calcium Sensor (NCS) duplication 英文论文文献.docVIP
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Two Frequenins in Drosophila unveiling the evolutionary history of an unusual Neuronal Calcium Sensor (NCS) duplication 英文论文文献
Sánchez-Graciaetal.BMCEvolutionaryBiology2010,10:54
/1471-2148/10/54
RESEARCH ARTICLE
OpenAccess
TwoFrequeninsinDrosophila:unveilingthe
evolutionaryhistoryofanunusualNeuronal
CalciumSensor(NCS)duplication
AlejandroSánchez-Gracia1,2*,JesúsRomero-Pozuelo1,3,AlbertoFerrús1
Abstract
Background:DrosophilaFrequenin(Frq),thehomologofthemammalianNeuronalCalciumSensor-1(NCS-1),isa
highaffinitycalcium-bindingproteinwithubiquitousexpressioninthenervoussystem.Thisproteinhasan
importantroleintheregulationofneurotransmitterreleasepersynapse,axonalgrowthandboutonformation.In
D.melanogaster,Frequeninisenco
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