Using mouse models to study function of transcriptional factors in T cell development 英文论文文献.docVIP
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Using mouse models to study function of transcriptional factors in T cell development 英文论文文献
Lietal.CellRegeneration2012,1:8
/content/1/1/8
REVIEW
OpenAccess
Usingmousemodelstostudyfunctionof
transcriptionalfactorsinTcelldevelopment
PengLi1,2*,YirenXiao1,2,ZhixinLiu1,2*andPentaoLiu3
Abstract
Laboratorymicehavewidelybeenusedastoolsforbasicbiologicalresearchandmodelsforstudyinghuman
diseases.Withtheadvancesofgeneticengineeringandconditionalknockout(CKO)mice,wenowunderstand
hematopoiesisisadynamicstepwiseprocessstartingfromhematopoieticstemcells(HSCs)whichareresponsible
forreplenishingallbloodcells.Transcriptionalfactorsplayimportantroleinhematopoiesis.Inthisreviewwe
compileseveralstud
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