原创力文档Variation in the IL1B, TNF and IL6 genes and individual susceptibility to prosthetic joint infection 英文论文文献.docVIP
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Variation in the IL1B, TNF and IL6 genes and individual susceptibility to prosthetic joint infection 英文论文文献
Stahelovaetal.BMCImmunology2012,13:25
/1471-2172/13/25
RESEARCH ARTICLE
OpenAccess
VariationintheIL1B,TNFandIL6genesand
individualsusceptibilitytoprostheticjointinfection
AnnaStahelova1,FrantisekMrazek1,MatejSmizansky2,MartinPetrek1andJiriGallo2*
Abstract
Background:Prostheticjointinfection(PJI)isanimportantfailuremechanismoftotaljointarthroplasty(TJA).Here
weexaminewhethertheparticulargeneticvariantscanleadtoincreasedsusceptibilitytoPJIdevelopment.
Results:Weconductedagenetic-associationstudytodeterminewhetherPJIcouldbeassociatedwithfunctional
cytokinegenepolymorphisms(CGP)influencingoninn
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