Whole-exome sequencing of DNA from peripheral blood mononuclear cells (PBMC) and EBV-transformed lymphocytes from the same donor 英文论文文献.docVIP

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Whole-exome sequencing of DNA from peripheral blood mononuclear cells (PBMC) and EBV-transformed lymphocytes from the same donor 英文论文文献.doc

Whole-exome sequencing of DNA from peripheral blood mononuclear cells (PBMC) and EBV-transformed lymphocytes from the same donor 英文论文文献

Londinetal.BMCGenomics2011,12:464 /1471-2164/12/464 RESEARCH ARTICLE OpenAccess Whole-exomesequencingofDNAfromperipheral bloodmononuclearcells(PBMC)andEBV- transformedlymphocytesfromthesamedonor EricRLondin1,MargaretAKeller2,MichaelRD’Andrea3,KathleenDelgrosso4,5,AdamErtel4,5,SaulSurrey6and PaoloFortina4,5,7* Abstract Background:Thecreationoflymphoblastoidcelllines(LCLs)throughEpstein-Barrvirus(EBV)transformationofB- lymphocytescanresultinavaluablebiomaterialforcellbiologyresearchandarenewablesourceofDNA.While LCLshavebeenusedextensivelyincellularandgeneticstudies,theprocessofcelltransforma

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