Antibiotic sensitivity pattern of common bacterial pathogens in NICU and neonatal ward in Hamedan province of Iran英文文献资料.docVIP

Vol.2, No.6, 625-629 (2010) Health doi:10.4236/health.2010.26094 Antibiotic sensitivity pattern of common bacterial pathogens in NICU and neonatal ward in Hamedan province of Iran Alireza Monsef , Fatemeh Eghbalian * 1 2 1 2 Pathology Department, Hamadan University of Medical Sciences, Hamadan, Iran Pediatric Department, Hamadan University of Medical Sciences, Hamadan, Iran; Corresponding Author: eghbalian_fa@ * Received 15 January 2010; revised 5 February 2010; accepted 8 February 2010. ABSTRACT 1. INTRODUCTION Bacterial pathogens and drug resistance are different in hospitals of each country. In this study we determined bacterial path- ogens and drug sensitivity in the neonatal ward and neo- natal intensive care unit (NICU) in Ekbatan hos- pital in Hamedan. This cross-sectional descrip- tive study was done on 1150 hospitalized neo- nates in neonatal and NICU wards of Ekbatan hospital of the Hamadan university of medical sciences from September 2004 to September 2006. Blood, cerebrospinal fluid (CSF), urine, stool, eye excretion, synovial fluid, umbilical secretion and ascitic fluid were evaluated. Posi- tive cultures were evaluated for antibiotic re- sistance with disk diffusion test methed. All of the data in questionnaires was analyzed with SPSS 13. Cultures including blood, urine, CSF , stool, eye excretion, synovial fluid, umbilical secretion and ascitic fluid was done in 417 neonates (833 cultures). These cultures were including: urine, 323 cases (38.8%) blood 293 cases (35.2%), CSF 180 cases (21.6%) , stool 17 cases (2%), eye secretion 16 cases (1.9%) and other secretions (synovial, umbilical, etc) 4 cases (0.5%). The cultures were positive in 105 cases (25.2%). 60 male neonates (57.1%) and 45 female neonates (42.9%) were culture positive. The most common microorganisms were E coli 66.