Antibacterial Properties of Nanosilver PLLA Fibrous Membranes英文文献资料.docVIP

HindawiPublishingCorporation JournalofNanomaterials Volume2009,ArticleID168041,5pages doi:10.1155/2009/168041 ResearchArticle AntibacterialPropertiesofNanosilverPLLAFibrousMembranes LinLi, YiLi, JiashenLi, LeiYao, ArthurF.T.Mak, FrankKo, andLingQin 1 1 1 1 2 3 4 1 2 3 4 InstituteofTextilesandClothing,TheHongKongPolytechnicUniversity,Kowloon,HongKong DepartmentofHealthTechnologyandInformatics,TheHongKongPolytechnicUniversity,Kowloon,HongKong DepartmentofMaterialsEngineering,AMPEL,TheUniversityofBritishColumbia,Vancouver,BC,Canada DepartmentofOrthopaedicsandTraumatology,TheChineseUniversityofHongKong,Shatin,HongKong CorrespondenceshouldbeaddressedtoYiLi,tcliyi@.hk Received15October2008;Revised13March2009;Accepted24April2009 RecommendedbyAlanK.T.Lau Nanosilverhasbeenstudiedasavaluablematerialforitstrongantibacteriale?ects.Inthisstudy,weinvestigatedtheantibacterial propertiesofnanosilverPoly-L-Lacticacid(Ag/PLLA)composite?brousmembranes.Ag/PLLA?brousmembraneswereprepared with silver nanoparticles having weight ratio of silver nanoparticles to PLLA at 5% (w/w). In vitro antibacterial tests were performed using Escherichia coli (E. coli) and Staphylococcus aureus (Staph.) to determine the antibacterial capability of the Ag/PLLA?brousmembranes.Astheresultssuggested,Ag/PLLA?brousmembranesshowedstrongantibacterialproperties.Thus, Ag/PLLA?brousmembranecanbeusedasanantibacterialsca?oldfortissueengineering. Copyright?2009LinLietal.ThisisanopenaccessarticledistributedundertheCreativeCommonsAttributionLicense,which permitsunrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalworkisproperlycited. 1.Introduction ?berstoprovideamatrixwithwideinterfaceforcombining antibacterialmaterials. Tissueengineeringsca?oldswhicharesupposedtobeused formedicalapplicationshaveappliedvariouspolymerssuch asdegradablePoly-L-Lactide(PLLA)andPolyglycolicacid (PGA), or natural biomaterials like chitin, silk, protein