Bayesian Integration of Isotope Ratio for Geographic Sourcing of Castor Beans英文文献资料.docVIP

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Bayesian Integration of Isotope Ratio for Geographic Sourcing of Castor Beans英文文献资料.doc

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Bayesian Integration of Isotope Ratio for Geographic Sourcing of Castor Beans英文文献资料

HindawiPublishingCorporation JournalofBiomedicineandBiotechnology Volume2012,ArticleID450967,8pages doi:10.1155/2012/450967 ResearchArticle BayesianIntegrationofIsotopeRatiofor GeographicSourcingofCastorBeans Bobbie-JoWebb-Robertson, 4 1 HelenKreuzer, GaryGill, andDouglasDuckworth 3 GarretHart, 2 3 JamesEhleringer, JasonWest, 5 6 1 2 3 4 5 6 ComputationalBiologyandBioinformatics,Paci?cNorthwestNationalLaboratory,Richland,WA99352,USA Biodefense,Paci?cNorthwestNationalLaboratory,Richland,WA99352,USA NuclearMaterialAnalysis,Paci?cNorthwestNationalLaboratory,Richland,WA99352,USA DepartmentofGeologyandGeophysics,TheUniversityofUtah,SaltLakeCity,UT84112,USA DepartmentofEcosystemScienceandManagement,TexasAMUniversity,CollegeStation,TX77843,USA MarineSciencesLaboratory,Paci?cNorthwestNationalLaboratory,Sequim,WA98382,USA CorrespondenceshouldbeaddressedtoBobbie-JoWebb-Robertson,bobbie-jo.webb-robertson@pnl.gov Received29February2012;Accepted13May2012 AcademicEditor:CarlosRamos Copyright?2012Bobbie-JoWebb-Robertsonetal. This is an open access article distributed under the Creative Commons AttributionLicense,whichpermitsunrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalworkis properlycited. Recentyearshaveseenanincreaseintheforensicinterestassociatedwiththepoisonricin,whichisextractedfromtheseedsof theRicinuscommunisplant.Bothlightelement(C,N,O,andH)andstrontium(Sr)isotoperatioshavepreviouslybeenused toassociateorganicmaterialwithgeographicregionsoforigin.WepresentaBayesianintegrationmethodologythatcanmore accuratelypredicttheregionoforiginforacastorbeanthanindividualmodelsdevelopedindependentlyforlightelementstable isotopesorSrisotoperatios.Ourresultsdemonstrateaclearimprovementintheabilitytocorrectlyclassifyregionsbasedonthe integratedmodelwithaclassaccuracyof60.9± 2.1%versus55.9± 2.1%and40.2± 1.8%forthelightelementandstrontium (Sr)isotoperatios,respectively.Inaddition,weshowgraphicallythestrengthsandweaknessesofeachdatasetinre