Case report Olanzapine-induced acute pancreatitis and new diabetes mellitus英文文献资料.docVIP

Open Journal of Psychiatry, 2012, 2, 110-112 OJPsych /10.4236/ojpsych.2012.22015 Published Online April 2012 (http://www.SciRP.org/journal/ojpsych/) Case report: Olanzapine-induced acute pancreatitis and new diabetes mellitus Erik Monasterio , Ruchi Bhalla , Andrew McKean 1* 2 3 1 2 3 Department of Psychological Medicine, University of Otago, Christchurch, New Zealand Hammersmith and Fulham Mental Health Unit, West London Mental Health NHS Trust, London, UK Hillmorton Hospital, Christchurch, New Zealand Email: erik.monasterio@t.nz * Received 29 December 2011; revised 31 January 2012; accepted 15 February 2012 ABSTRACT criteria and required application from a psychiatrist for a patient who had been trialled unsuccessfully on risperi- done or required treatment with olanzapine short acting intra-muscular injection [4]. In June 2011, significantly cheaper generic versions of olanzapine were introduced and the special authority criteria for olanzapine with- drawn [5]. We aim to highlight lesser known and poten- tially fatal side effects through our case report. The aim of this case study is to review the literature and report the first published case of olanzapine-in- duced acute pancreatitis in New Zealand. A case re- port of acute pancreatitis with new onset diabetes mellitus secondary to olanzapine in a 42-year-old male, in the absence of medical risk factors is reported. Eleven previous case reports of olanzapine induced acute-pancreatitis were identified in the literature. A 42-year-old male was diagnosed with acute pancreati- tis and new diabetes mellitus induced by olanzapine. Although rare, pancreatitis is associated with use of some atypical antipsychotic medications. It is impor- tant for prescribers to be aware of this potentially fatal side effect. In addition to this, we are highlight- ing